[Eosinophilic fasciitis after taking simvastatin].

The characteristic vascular pattern may include irregular, arborizing, tortuous, or dotted vessels. Some authors consider these vascular structures specific for Bowen disease 3,9,10 and designate them glomerular vessels 10 in view of their particular morphology and their resemblance to vessels of the renal glomerulus. According to those same authors, these vascular structures are similar to the dotted vessels that may be present in amelanotic melanoma, although, in the case of Bowen disease, these structures are larger and have a helical morphology. The pigmented forms of Bowen disease, in addition to the aforementioned criteria, are characterized by the presence of globules (90%) and homogeneous areas of grayish-brown pigmentation (80%). 3 These globules are usually smaller than those associated with melanocytic lesions and characteristically follow a patchy distribution in some parts of the lesion. In the case that we present here, 3 of the 4 dermoscopic criteria for pigmented Bowen disease (atypical vascular pattern, squamous or verrucous surface, and patchy distribution of globules) were met. However, we were unable to confirm the presence of specific glomerular vessels and found instead an atypical vascular pattern. Despite the usefulness of the dermoscopic criteria for diagnosing Bowen disease, we should highlight that all of them may be present in benign melanocytic tumors, seborrheic keratosis, basal cell carcinomas, and melanoma. For this reason, we believe that they are not completely reliable for a correct differential diagnosis with other pigmented lesions, and particularly with melanoma. Histology remains the gold standard for an accurate differential diagnosis. The case we present here reflects the complex nature of diagnosing skin tumors, particularly when they present with clinical and dermsocopic characteristics common to several other tumors at an age when they are uncommon and at an unusual site. disease mimicking cutaneous malignant melanoma: Clinical and dermoscopic aspects. (squamous cell carcinoma in situ): A mimic of malignant melanoma.s disease and review of 420 Bowen's disease lesions. To the Editor: Eosinophilic fasciitis is a rare fibrosing disease characterized by painful, symmetric inflammation of the limbs, and progressive induration of the skin. In some cases, it can also lead to debilitating joint contractures, arthritis, neuropathy, and myositis. The hallmark histologic finding is fascial fibrosis. While eosinophilic fasciitis is considered by some to be a variant of morphea or scleroderma, others believe it to be a separate entity. The condition is of unknown etiology but it has been associated with a variety of disease processes …